>BME Track 2

Tissue Engineering and Drug Delivery System Track

http://www.eg.mahidol.ac.th/dept/egbio/data/research_en/track2.html

Tissue engineering definition:

From Wikipedia, the free encyclopedia

Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physio-chemical factors to improve or replace biological functions. While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bioartificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells to produce tissues

See details:>>http://en.wikipedia.org/wiki/Tissue_engineering#Overview

Drug delivery

From Wikipedia, the free encyclopedia

Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals[1] [2]. Drug Delivery technologies are patent protected formulation technologies that modifies drug release profile, absorption, distribution and elimination for the benefit of improving product efficacy & safety and patient convenience & compliance[3]. Most common methods of delivery include the preferred non-invasive peroral (through the mouth), topical (skin), transmucosal (nasal, buccal/sublingual, vaginal, ocular and rectal) and inhalation routes [4][5]. Many medications such as peptide and protein, antibody, vaccine and gene based drugs, in general may not be delivered using these routes because they might be susceptible to enzymatic degradation or can not be absorbed into the systemic circulation efficiently due to molecular size and charge issues to be therapeutically effective. For this reason many protein and peptide drugs have to be delivered by injection. For example, many immunizations are based on the delivery of protein drugs and are often done by injection.

Current efforts in the area of drug delivery include the development of targeted delivery in which the drug is only active in the target area of the body (for example, in cancerous tissues) and sustained release formulations in which the drug is released over a period of time in a controlled manner from a formulation.

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 Elective Courses :

  Credits (lecture-lab-self study)

Tissue Engineering and Drug Delivery System Track  

EGBE   619  Biology for Engineers  3(3-0-6)

EGBE   630  Cell and Tissue Engineering   3(3-0-6)

EGBE   631  Advanced Drug Delivery   3(3-0-6)

EGBE   632  Physiological Transport Phenomena  3(3-0-6)

EGBE   633  Biomedical Polymers  3(3-0-6)

EGBE   634  Biomaterials and Biocompatibility   3(3-0-6)

EGBE   635  Materials for Biomedical Applications   3(3-0-6)

EGBE   670  Biochemistry for Biomedical Engineering  3(3-0-6)

EGBE   671  Nanobiotechnology  3(3-0-6)

EGBE   680-689    Special Topics in Biomedical Engineering   3(3-0-6)

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